Efficacy Tests

For Your Individual Claim Support

National and international legislations on cosmetics require that every efficacy claim of cosmetic products such as long-lasting moisturization and anti-aging effects should be substantiated scientifically.
We are equipped with state-of-the-art biophysical instruments to substantiate not only standard claims related to skin moisture and elasticity on healthy skin but also specific claims in the field of problematic skin (e.g. impure facial skin) as well as on scalp, hair, nails and much more.

In the following, you will find a list of parameters and instrumentation that may be of interest for your individual claim support:

Standard Biophysics

  • Skin moisture (Corneometer®, SkiCon®, DermaLab®)
  • Skin roughness (silicon imprints, Primos® in vivo)
  • Skin scaliness (D-Squames®, analysis with SquameScan®)
  • Skin elasticity (Cutometer®, Torquemeter®, Ballistometer®)
  • Reduction of eye wrinkles and fine lines (Primos®)
  • Skin whitening, effects on melanogenesis (Siascope®, Mexameter®, Spectrophotometer®)
  • Structure of the dermis such as dermis density and thickness (Ultrasound with DermaScan® C, Primos® in vivo):
    Analysis of dermis density and thickness

Evaporative Waterloss (DermaLab®, Aquaflux®)

  • Skin barrier integrity (trans epidermal water loss, TEWL)
  • Trans onycheale water loss on fingernails (TOWL)
  • Water holding capacity: Plastic Occlusion Stress Test (POST), Skin Surface Water Loss (SSWL)
  • Skin resilience following tape stripping

Lipid Barrier (Lipbarvis® / TEM)

Photo Documentation

  • FotoFinder® mediscope studio consisting of:
  • Canon Powershot digital camera
  • FotoFinder® mediscope software
  • Lens D-Scope I (microphotography, 7-35x magnification)
  • Lens D-Scope II (macrophotography, 40x magnification)
  • Veinscope with polarization filter and custom-built spacer with integrated color range
  • Portrait stand
  • VISIA-CR® System (portrait)

Impure Facial Skin

  • Sebum production (Sebumeter®, Sebupatch®)
  • Skin surface shine (Glossymeter®)
  • Acne reduction: lesion count, lesion size and redness (visual assessment, Colorimetry/Spectrophotometer®, Mexameter®, VISIA-CR®, FotoFinder® System)
  • Deep-pore cleansing effect of cosmetic products and/or devices (high-resolution photography and expert assessment):
    High resolution photography

Scalp, Hair & Nails

  • Skin moisture at the scalp (DermaLab®)
  • Hair growth (trichogram, length and thickness)
  • Keratolytic properties (anti-dandruff)
  • Nail growth and quality (brittleness, histology, leukonychia etc.)
  • Transonycheale water loss on fingernails (TOWL, DermaLab®)
  • Photo documentation

Additional Special Parameters

  • Subjective evaluation of product performance
  • Anti-pollution as UV/smoke model(analyis of markers such as MMPs and/or interleukins (ELISA) or analysis of the lipid barrier (REM, TEM, HPTLC, in cooperation with Microscopy Services Dähnhardt GmbH)
  • Anti-inflammatory effects (UV erythema model)
  • Microbiom analysis in cooperation with Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB
  • Axillary studies (shaving, visual assessment)
  • Deodorant effects (sniff test)
  • Peeling (exfoliating) effect
  • Shaving / depilation / epilation procedures
  • cleansing efficacy of cosmetics / cosmetic devices
  • Diaper studies (newborns and babies)
  • Oral food supplement studies (e.g. cellulite by ultrasound measurements and Primos® in vivo)
  • Rinse-off studies (short- and long-term kinetics)
  • Leave-on studies with kinetics and regression phases
  • Regenerative effect / cell renewal (DHA method)
  • Natural moisturizing factor (e.g. urea analytics)
  • Biochemical / molecular biological analysis

Dermatological Mode of Action (in vivoex vivoin vitro)

  • Non-invasive via suction blister biopsies (e.g. collagen, interleukines, oxidative stress, cell proliferation, stem cell activity, histology etc.)
  • Invasive via punch biopsies (e.g. histology, molecular biology etc.)

Please contact us for further information, consultation or a detailed proposal.